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Assess specificity and off-target binding of your biotherapeutic candidates. De-risk your program and choose the right lead molecule.
The Membrane Proteome Array is the leading solution for antibody specificity profiling. Our cell-based array contains the largest set of human membrane proteins (including heterocomplexes) assembled to determine specificity and preclinical safety of antibodies, CAR-T cell therapies, and other biotherapeutics.
“MPA technology quickly provided us with the reassurance that Abound Bio’s potent neutralizing antibodies to SARS-CoV-2 did not bind off-target human membrane proteins, which could be associated with toxicity.”
-John W. Mellors, MD, CEO, Abound Bio
“We have been very pleased with the data that we obtained from the Membrane Proteome Array platform. This showed that our antibodies recognize only their select target, and not other membrane proteins in their panel.”
-MARIA GONZALEZ-PAJUELO, CSO, FAIRJOURNEY BIOLOGICS
6,000 membrane proteins (including heterocomplexes)
representing >94% of the membrane proteome
The Membrane Proteome Array uses the largest membrane protein library ever assembled, flow cytometry, and unfixed cells for high-sensitivity detection, resulting in the broadest screens and the highest success rates. A typical project involves:
FAQ Question about ISTAND:
What does the MPA’s qualification under the FDA’s ISTAND Program mean for me?
Our MPA+IND service provides antibody specificity testing and safety profiling information for your IND applications. Through ISTAND, we are working with the FDA toward streamlining your regulatory review process. To learn more, visit MPA Accepted for Consideration under FDA’s ISTAND Program
We have worked with more than 100 top biotech and pharmaceutical companies to help them succeed. Let’s talk about how we can help you.
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