THE INDUSTRY LEADER IN MEMBRANE PROTEIN SOLUTIONS

Integral Molecular Enters into Antibody License Agreement with AstraZeneca for Oncology Therapeutics
11/3/2021

Integral Molecular and Integrated BioTherapeutics Collaborate to Engineer Broadly Protective Ebolavirus Vaccines
11/2/2021

6th International Conference on Vaccines, Research & Development
November 1-2 | Virtual
 

Webinar: Combatting SARS-CoV-2 Variants: Neutralization Testing from Alpha to Mu
November 30 | Virtual

 

Neutralizing and protective human monoclonal antibodies recognizing the N-terminal domain of the SARS-CoV-2 spike protein
Cell, 2021

Molecular determinants and mechanism for antibody cocktail preventing SARS-CoV-2 escape
Nature Communications, 2021

THE INDUSTRY LEADER IN MEMBRANE PROTEIN SOLUTIONS

Why Are There So Few Therapeutic Antibodies Against Complex Membrane Proteins?

Multi-spanning membrane proteins are targets of half of all small molecule drugs but only 3 therapeutic monoclonal antibodies (MAbs).

drug targets

MAbs offer therapeutic advantages of exquisite specificity, safety, and bioavailability and are twice as likely as small molecules to succeed in clinical trials. However, due to the complex structure and high homology of membrane protein targets, MAbs against them are difficult to generate, isolate and characterize.

Integral Molecular Enables Membrane Protein Antibody Discovery

With a 95% success rate, Integral Molecular is the leader in isolating MAbs against complex membrane proteins, including GPCRs, ion channels, transporters and viral proteins.

INDUSTRY EXPERIENCE

With 15+ years experience, Integral Molecular is the industry leader in isolating and characterizing complex membrane proteins.

PROVEN QUALITY

Integral Molecular’s technologies have contributed to scientific discoveries featured in 200+ peer-reviewed publications.

OPEN COMMUNICATION

Your success is crucial to us. We work hard to understand your needs, and strive to exceed your expectations.

Membrane Protein Solutions

Our full suite of Membrane Protein Solutions delivers diverse panels of functional MAbs
Our virus-like particles contain high levels of native membrane proteins for better immunization and screening
Our Ala-scan epitope mapping service provides mechanism of action data and strengthens IP
We screen antibodies against 6,000 human membrane proteins for deorphaning and de-risking studies
We provide innovative tools, including Reporter Virus Technology, for rapid immunocharacterization
We offer licensing opportunities for therapeutic antibodies against untapped targets

200+ Publications Including Cell, Science & Nature

Trusted by 300+ Companies

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We have worked with more than 100 top biotech and pharmaceutical companies to help them succeed. Let’s talk about how we can help you.