THE INDUSTRY LEADER IN MEMBRANE PROTEIN SOLUTIONS

Integral Molecular and Optimeos Life Sciences Enter Partnership to Develop mRNA and DNA-Based Gene Therapies Using Molecular Targeting
6/8/2022

Integral Molecular Breaks Ground on New Headquarters, Doubling in Size
5/24/2022

 
Genetic Engineering Webinar: Towards IND: Specificity Profiling of Antibody-Based Therapies
July 14 | 11 am ET
 

Sites of vulnerability in HCV E1E2 identified by comprehensive functional screening Cell Reports, 2022

Broadly neutralizing antibodies target the coronavirus fusion peptide Science, 2022

THE INDUSTRY LEADER IN MEMBRANE PROTEIN SOLUTIONS

Why Are There So Few Therapeutic Antibodies Against Complex Membrane Proteins?

Multi-spanning membrane proteins are targets of half of all small molecule drugs but only 3 therapeutic monoclonal antibodies (MAbs).

drug targets

MAbs offer therapeutic advantages of exquisite specificity, safety, and bioavailability and are twice as likely as small molecules to succeed in clinical trials. However, due to the complex structure and high homology of membrane protein targets, MAbs against them are difficult to generate, isolate and characterize.

Integral Molecular Enables Membrane Protein Antibody Discovery

With a 95% success rate, Integral Molecular is the leader in isolating MAbs against complex membrane proteins, including GPCRs, ion channels, transporters and viral proteins.

INDUSTRY EXPERIENCE

With 20+ years experience, Integral Molecular is the industry leader in isolating and characterizing complex membrane proteins.

PROVEN QUALITY

Integral Molecular’s technologies have contributed to scientific discoveries featured in 350+ peer-reviewed publications.

OPEN COMMUNICATION

Your success is crucial to us. We work hard to understand your needs, and strive to exceed your expectations.

Membrane Protein Solutions

Our full suite of Membrane Protein Solutions delivers diverse panels of functional MAbs
Our virus-like particles contain high levels of native membrane proteins for better immunization and screening
Our Ala-scan epitope mapping service provides mechanism of action data and strengthens IP
We screen antibodies against 6,000 human membrane proteins for deorphaning and de-risking studies

Reporter Virus Particles and other tools to expedite vaccine and antibody development

We offer licensing opportunities for therapeutic antibodies against untapped targets

350+ Publications Including Cell, Science & Nature

Trusted by 400+ Companies

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We have worked with more than 100 top biotech and pharmaceutical companies to help them succeed. Let’s talk about how we can help you.