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Please submit your resume and cover letter to careers@integralmolecular.com with the Job ID# in the subject heading. Integral Molecular is an Equal Opportunity Employer.
ABOUT INTEGRAL MOLECULAR
Integral Molecular is a research-driven biotechnology company creating innovative technologies and therapeutic antibodies for under-exploited membrane protein targets, including GPCRs, ion channels, transporters, and viral envelopes.
20+ years experience optimizing membrane proteins
Work with Top 20 pharmaceutical companies
400+ customers and partners
Are you passionate about science and interested in joining a world-class research team?
Do you want to be a part of a close-knit, small company that takes an active interest in your learning and development?
We are looking for smart, curious, and passionate individuals to join our team and contribute to our shared success.
What you can expect:
- Serious work in a casual atmosphere
- Collaborative, dynamic learning environment
- New ideas and constant innovation
- Leadership opportunities to enable your career
- Scientifically and culturally diverse teams
How To Apply To Integral Molecular
Please submit your resume and cover letter to careers@integralmolecular.com with the Job ID# in the subject heading. Integral Molecular is an Equal Opportunity Employer.
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Current Career Openings
Research
Our company is in an exciting growth phase where we are launching new products, expanding our team, and reaching new markets. We seek a Research Scientist to join our team of virologists and cellular biologists to create pseudoviruses used in the development of therapeutic antibodies and vaccines. Our reporter virus product is a vital reagent in the global response to new, emerging, and evolving viral threats. You will use your expertise to lead efforts in research and development, continuous improvement, and production.
You will also be responsible for identifying and championing new ideas and process improvements that enhance the operations within the virology team. To advance our R&D programs, you will work with the scientific and business teams to understand customer needs and create roadmaps for new product development.
Additionally, you may supervise and provide scientific guidance and mentorship to junior researchers within the team. The ideal candidate will be comfortable working in a fast-paced, collaborative environment focused on meeting customer deadlines and will also have a passion for developing new technical expertise from assay development to routine execution of projects.
Opportunities:
- Growth as a scientific leader within a supportive, research-focused learning environment
- Drive new product development from idea to market
- Foster client relationships as you become a SME in virology
Responsibilities:
- Independently design, execute, and analyze cell-based assays for custom virology products in collaboration with internal and external stakeholders
- Independently design, execute, and interpret quality control assays and data for current and new pseudoviruses, including method development, lot release, and stability testing
- Propose and implement solutions for areas of improvement in current reporter virus production and QC assays
- Collaborate with the team to prepare the final report for delivery to customers
- Substantively contribute to the preparation of materials for internal and external presentations and conferences
- Actively create and maintain mentor relationships with junior members of the team by providing technical and scientific guidance
- Acquire new skillsets as needed and apply existing skillset in new and creative ways
Qualifications:
Education:
- PhD in Biology, Chemistry, Biochemistry or a related field
- Basic knowledge in immunology or virology is desired
Experience:
- Proven track record of achievement in cell biology, virology, or related disciplines through peer-reviewed publications and presentations
- Strong background in biological cell-based assay development, optimization, troubleshooting, and validation is required
- Familiarity with flow cytometry, luciferase assays, and viral or pseudoviral particle production (propagation, neutralization assays, etc) is a plus
- Demonstrated ability to work within a team and as a highly successful individual contributor
Integral Molecular is an Equal Opportunity Employer with a deep commitment to promoting a diverse, respectful, and inclusive workplace.
Our company is in an exciting growth phase where we are launching new products, expanding our team, and reaching new markets. We seek a deeply scientifically curious scientist to join a diverse, interactive, collaborative, and highly supportive antibody discovery research team. The Research Scientist, under the supervision of the VP Antibody Discovery (or Director of Research), will join our team of scientists in antibody discovery to analyze and synthesize information and data about new drug targets and antibody-related technologies. The Research Scientist will analyze scientific literature, patents, and databases to assess project risks and develop risk mitigation strategies and solutions. The assessments will contribute to evidence-based decision making about feasibility of proposed projects and partnerships as well as development of research plans and support of the execution with analysis and data interpretation.
In addition, this role will interact with external customers and partners to understand their projects and provide scientific guidance on appropriate scope of work using Integral Molecular’s technologies and platforms.
Integral Molecular supports employee work/life balance and this position can be hybrid with work hours divided between working onsite and working remotely.
Opportunities:
- Enable your transition from academic research to biotech/industry science
- Develop insights into business models for product delivery in virology, antibody, and pre-clinical spaces
- Involvement in high impact research in drug discovery/biologics
- Develop cutting edge technologies in MAb discovery
- Learn the antibody drug discovery process
- Learn high-throughput cloning approaches
Responsibilities:
- Generate risk analysis for new projects by reviewing relevant internal and published data for membrane protein discovery and other targets; analyze and translate this data to generate insights and drive actions for drug discovery
- Design reporter and expression plasmid constructs to mitigate risks for the expression of membrane and viral proteins in support of customer projects and development of internal research priorities
- Design experiments and guide troubleshooting for testing reporter and expression constructs
- Collaborate extensively with internal and external teams to ensure discovered antibodies meet customer and internal requirements
- Develop and deliver scientific presentations for internal meetings, customer calls and conferences
- Keep abreast of new scientific/technology development related to antibody discovery, high throughput cell-based analysis platforms, and other topics by participating in scientific meetings/seminars and through regular scientific review
- Provide technical expertise on sales calls
- Teach, train, and provide guidance and support to junior team members in laboratory experiments and scientific development
Qualifications:
Education:
- PhD in Cell Biology, Biochemistry, Bioinformatics, Molecular Biology, Chemical or Biological Engineering, Virology or a related field
- Postdoctoral experience is preferred
- Basic knowledge in immunology or virology is desired
Experience:
- Extensive prior experience with plasmid design, construction, and lab-based execution of those designs
- Experience with heterologous or recombinant membrane protein expression
- Familiarity with flow cytometry, phage display, antibody production, and/or viral particle production
- Proven track record of excellent scientific judgement and sound decision-making
- Demonstrated ability as an individual contributor and evidence of the ability to work cooperatively within a team
- Creative problem-solving and analytical skills that impact project outcomes
- Excellent verbal and written communication skills
- Experience in the biotech/pharma industry is a plus
Integral Molecular is an Equal Opportunity Employer with a deep commitment to promoting a diverse, respectful, and inclusive workplace.
Our company is in an exciting growth phase where we are launching new products and reaching new markets. To support our growth, we seek a Research Associate I, who will work with a dedicated group of scientists on the development and commercialization of biomedical technologies.
Opportunities:
Opportunities:
- Develop high throughput protein and antibody characterization skills
- Develop molecular design and engineering skills along with high-throughput molecular cloning skills
- Scientific development leading to professional advancement or Graduate School
- Conduct laboratory research and support general R&D efforts for customer-based biomedical research
- Projects may involve cell culture, virology, DNA preparation, and liquid-handling automation
- Perform molecular biology (PCR, E.coli transformation, Sanger sequencing and analysis, primer and plasmid design) or cell-based assays (Western blot, ELISA, immunofluorescence, flow cytometry)
- Minimum of a bachelor’s degree in biology, bioengineering, or a related field is required
- 1–2 years of laboratory and cell-culture experience is desired
- Demonstrated ability to follow protocols and learn quickly
- Candidates must be attentive to detail
- Ability to work in a team-based environment with a collaborative and proactive attitude
Are you comfortable with complex co-cultures using primary/immortal cell lines? Does your research involve understanding signaling molecules related to the immune response using fluorescence-based methods?
We want you to, over the next 18 months, drive the development of a high-throughput screening (HTS) platform that identifies adjuvant candidates and targets in response to an antigen. You will do this using our antibody screening and deconvolution platform (Membrane Proteome Array).
Integral Molecular is a Philadelphia biotech company specializing in the discovery and characterization of therapeutic antibodies using cutting-edge technology platforms. We are a clos-knit company composed of smart, curious scientists that takes an active interest in platform that allows for promoting the learning and development of our team. Our company is in an exciting growth phase that involves the development of innovation solutions for antibody development and vaccine discovery.
Opportunities:
- Drive the development and implementation of new technology platforms to support the development of therapeutic antibodies and vaccines.
- Discover novel receptors and drug targets for diseases including cancer, aging, and auto-immunity.
- Identify novel targets to be used for adjuvant development.
- Use your expertise to assess the specificity and selectivity of biotherapeutics going into preclinical trials.
- Become a scientific leader within a rapidly growing team
Responsibilities:
- Plan and execute on immunology related R&D
- Design and execute assays aimed at understanding signal transduction and receptor expression using flow cytometry and other fluorescence-based cellular assays.
- Design, implement and validate high throughput cellular assays for novel therapeutic target discovery using immortalized cell lines, primary human cell culture and cell co-culture methods
- Simultaneously lead multiple lines of research for internal and external clients.
- Lead and mentor junior scientists in the lab
Qualifications:
- Candidates should have a PhD in cell or molecular biology, immunology or a related discipline.
- Extensive experience working with both primary and immortalized human/murine cell lines. Experience with complex primary cell culture is preferred.
- Demonstrated ability to develop, execute, analyze and troubleshoot cell-based assays in plate-based formats
- Experience with immunological cellular assays is a plus
- Qualified candidate will have an innovative mindset, be a collaborative team player, effective critical thinker, clear communicator, and possess excellent troubleshooting skills.
A resume and cover letter should be sent with Job ID# 07052022 in the subject heading.
Administrative and Operations
Are you an entrepreneur at heart? Do you constantly want to learn and excel when you wear many hats? Our company is in an exciting growth phase where we are launching new products, expanding our team, and reaching new markets. We have doubled in size (about 50 to 100 employees) and our finance and admin teams are building strong foundations to keep pace with that growth. We seek a Finance and Administration Manager with an entrepreneurial mindset to lead these teams and be responsible for the day-to-day management of their activities. This position reports directly to the CEO and will support the management of the company and individual business units. Responsibilities will be both hands-on and managerial. Integral Molecular supports employee work/life balance with flexible work hours and telecommuting options; this position is expected to be on site about half time.
Opportunities:
- Use and learn skills beyond what you already know as you take on larger responsibilities
- Help start and grow new business units
- Work in a friendly, supportive environment with a flexible work schedule
Responsibilities:
Finance and Accounting
- Oversee AP and AR
- Approve payments, invoices, and allocations
- Administer NIH grants and contracts
- Coordinate internally and externally with tax, auditors, and advisors
- Manage banking, finance, and reconciliation activities
Administration and Human Resources
- Oversee admin and HR teams
- Oversee facilities operations
- Keep and update personnel records
- Prepare, enter, and administer payroll
Business Management
- Support corporate structuring and business unit management
- Help new business units start and become independent
- Analyze business performance and product line P&L
- Administer purchasing budgets, allocations, and negotiate pricing
- Support business units, sales, and marketing with budgeting and forecasting
Qualifications:
- Qualified candidates should have a demonstrated history of entrepreneurial activities, managing a team, and an interest in learning and growing
- Mastery of QuickBooks, Excel, and MS Office are required
- Aggressively detail-oriented with expert analytical thinking skills
- Supervisory experience is required
- Experience with non-profit NIH grants/contracts management is helpful but not required
- An understanding of scientific research is useful but is not required
- BA/BS; MBA, CPA, or MS in a business field preferred
Our company is in an exciting growth phase where we are launching new products and reaching new markets, and our finance and admin teams are building strong foundations to keep pace with that growth. We seek a Controller with an entrepreneurial mindset to be responsible for the day-to-day management of financial and accounting activities. Integral Molecular supports employee work/life balance with flexible work hours and telecommuting options; this position is expected to be on site about half time.
Opportunities:
- Learn new skills and take on new responsibilities
- Work in a friendly, supportive environment with a flexible work schedule
- Help start and grow new business units
Responsibilities:
Financial and Accounting
- A/P and A/R oversight
- Cash flow management
- Banking activities
- Financial reconciliations
- Budgeting and financial planning
- Coordination with external accountants and auditors
- Coordination with tax authorities
- NIH grants/contracts financial management and reporting
Administrative and Procurement
- Oversee ordering/purchasing, controlling costs, and actively seeking cost savings
- Administer purchasing budget, including both laboratory and office supplies
- Payroll and G&A allocations
- Monitor expense performance
- Negotiate pricing agreements with vendors
- Obtain bids for large dollar item purchases
- Implement internal controls for risk management
Qualifications:
- Qualified candidates should have an interest in learning and growing in an entrepreneurial environment
- Aggressively detail-oriented with expert analytical thinking skills
- Mastery of QuickBooks, Excel, and MS Office are required
- BA/BS; MBA, CPA, or MS in business field preferred
- Experience with non-profit NIH grants/contracts management is desired but not required
- An understanding of scientific research is useful but not required
If you are interested in this position, please send a resume and cover letter specifying your salary requirements to careers@integralmolecular.com.
We are seeking an entry-level Product Manager to enable the growth of our products, services, and technologies. You will accomplish these tasks by integrating an understanding of customer needs & challenges, the current & emerging market landscape, and internal capabilities & potential. Collaboration and the ability to work cross-functionally with multiple teams is at the core of this role. The product manager will interact with sales, marketing, business development, commercial, scientific, and leadership teams to provide strategic oversight to develop, launch, and grow new product offerings and solutions. Our product managers work in a fast-paced environment. They are organized, can dynamically prioritize short-term and long-term business needs and are driven to work at the intersection of science and business.
Opportunities:
- Develop and write business plans and strategize new product launches and continued company growth
- Work with executive leadership and a dedicated group of smart scientists committed to impacting the biomedical community and patient health, all in a friendly and supportive work environment
- Bring new technologies to market that will impact patients, the COVID-19 pandemic, and new areas of biomedical research
- Take on management duties that will extend your career and enable you to grow your experiences
- Training, mentorship and coaching from leadership
- Be a key part of a team that values new ideas, flexibility and has a passion for innovation
- Work in a growing biotech company launching innovative technologies
Responsibilities:
- Analyze and incorporate key market trends, customer feedback within all relevant segments, pricing strategy, and competitive offerings for the development of the product’s commercialization strategy and business model
- Develop and implement product strategy and product roadmap, in close collaboration with the customer, commercial, scientific, and leadership teams, to ensure product development and growth
- Lead efforts to identify new product directions based on customer feedback and work across functions to prioritize business opportunities that meet strategic objectives
- Create effective and integrated strategies, plans, and tactics to grow/expand current products and to launch new products.
- Collaborate with the marketing team to execute on marketing initiatives (content development, customer engagement and experience, lead generation) that deliver against product, business, and performance metrics.
- Serve as product champion with internal stakeholders, and with customers including key accounts.
- Garner deep customer insights and be the voice of the customer to evolve existing products and develop of new products
Qualifications:
- Master’s Degree/PhD in life sciences and/or business required
- Professional work experience in life science, biopharma, and/or business is a plus
- Excellent organizational, time-management, and communication skills including oral, written, and interpersonal skills
- Ability to be flexible to newer approaches and changing priorities– comfortable pivoting to meet the moment
- Strong stakeholder management at all levels of the organization
- Ability to identify solutions to meet evolving product and company priorities.
- Passionate, results-oriented, and motivated by team success
Internships
Integral Molecular offers part-time and temporary positions to scientists looking to transition from the bench to business. Our commercial internships are open to scientists with an interest and initial experience in learning the commercial side of science. You will work with our marketing, sales, business development, and product management teams. Projects can include market research, researching new product potential, and strategic planning. Commercial internship positions are flexible in nature, both in time and location. The positions are generally not paid but have the potential to turn into consulting or full-time positions at Integral Molecular.
Opportunities:
Benefits:
- Learn about biotechnology and opportunities in science outside of research
- Work with collegial, innovative, and intellectually stimulating team members in the development of new commercial products
Qualifications:
Scientists with a demonstrated interest in business, strategy, and commercialization are encouraged to apply
- Graduate students and post-docs are welcome (advisor approval may be required)
- A degree or enrollment in a biological degree program at the MS/PhD level is required
- Internships require a minimum of 5-10 hours/week of effort
- Internship projects typically encompass 2-3 months of work
- Successful candidates will be entrepreneurial and self-starting
- Excellent organization and communication skills are required
- Demonstrated interest or experience in business is desired, but prior business experience is not required
“Friendly culture and sense of community”
Working at Integral Molecular has provided me valuable learning and leadership opportunities in an innovative, supportive, and fun environment. I have been able to grow from an entry-level position to a management position while still being challenged with new and interesting projects. My colleagues make it easy to show up at work with a smile every day!
– Rachel Fong, Project Leader
