Tools and services for vaccine and therapeutic antibody developers

Critical virology reagents

20+ years virology expertise

Trusted by 100+ labs

Virology at Integral Molecular: Experience and Quality You Can Rely On

Integral Molecular is an experienced provider of virology reagents and services. We support scientists working to understand and combat diverse viruses, including influenza, SARS-CoV-2, dengue, Zika, Chikungunya, Ebola, Marburg, Nipah, and more.

Our flagship product is Reporter Virus Particles (RVPs). These non-replicative particles are a safe, ready-to-use substitute for live virus in infectivity and neutralization assays.

Explore: Virology Products & Services

Pseudotyped viral particles for safe, easy neutralization assays
Ready-to-use influenza reagent for easier hemagglutination inhibition (HAI) assays
For antibody developers who need neutralization data

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Custom pseudoviruses with the surface proteins and reporter of your choice

Trusted by 100+ Laboratories for R&D and Clinical Trials ​


The Integral Advantage: What Sets Us Apart


Integral Molecular was founded by virologists in 2001. We understand viruses from basic mechanisms to assay development. From Epitope Mapping to Lipoparticles and beyond, virology remains at the core of everything we do.


Because assays should be reliable and useful, we invest our time in making products that work well in your hands. To see our ISO 9001 certificate and a full description of our commitment to quality, please visit our Quality page.

Customer Experience
Your success is our priority, and we work hard to understand your needs. You get the products and services you expect, when you expect them.

“SARS-CoV-2 RVPs really helped us a lot since we did not have much previous expertise in SARS. The user meetings were especially helpful.”

Featured Publications

To see more publications, plus case studies and webinars, visit the Resources page

Our virology reagents are available directly through Integral Molecular or through our partner distributors.

Integral Molecular does not work with any live viruses capable of causing infectious disease. We have developed Reporter Virus Particles and other reagents to enable scientists to study viral components without the risk of exposure to viruses or the spread of contagious illnesses

Frequently Asked Questions

RVPs incorporate virus-specific envelope proteins that are antigenically equivalent to those of live wild-type viruses. They contain a modified genome and so are replication-incompetent and safe to use under standard safety levels (BSL-2). Once the RVPs are in your hands, you can begin your neutralization assays immediately – no need for growing and sequencing live virus.
RVPs are used for infectivity and neutralization assays, and are ideal for use in high-throughput assay formats. They are a safe (BSL-2) and efficient alternative to live virus plaque or microneutralization assays. Many customers use our RVPs to conduct sera neutralization assays to assess efficacy of their vaccine or vaccine candidate.
Luciferase and GFP are used for quantitative readouts.

Integral Molecular offers many vaccine development solutions including the production of reporter viruses, epitope mapping on viral targets, protein engineering for vaccine discovery, and antibody discovery against viral targets.

Yes. We can produce custom RVPs to accelerate your vaccine or antibody development project, with variants of current RVPs, or for a virus of your choice. We have a team of expert scientists that acts as your partner from project initiation to delivery of RVPs. Our customized quality control services and reports meet the specific needs of your team and project.

Yes. We can produce large lots of RVPs to accommodate screening 100s or 1000s of samples in sera neutralization assays without bridging studies.

Ready To Get Started?

We have worked with more than 100 top biotech and pharmaceutical companies to help them succeed. Let’s talk about how we can help you.

Or call (215) 966-6061