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PHILADELPHIA – Integral Molecular, the leader in discovering antibodies against multipass membrane proteins, announces fully optimized, high-affinity lead monoclonal antibodies (MAbs) against Claudin 18.2 (CLDN18.2), a structurally complex oncology target overexpressed on numerous solid tumors. The CLDN18.2 antibodies discovered using the company’s MPS antibody discovery platform are ready to progress towards preclinical studies and are … Read more

PHILADELPHIA – JOINN Laboratories, China’s leading preclinical contract research organization (CRO), has partnered with Integral Molecular to provide researchers in China with rapid antibody specificity testing against the entire human membrane proteome using Integral Molecular’s Membrane Proteome Array (MPA) technology. The ability to select lead candidates with high specificity will reduce safety liabilities prior to … Read more

The long-held assumption that antibodies are exquisitely specific is being re-examined since 25% of monoclonal antibodies (MAbs) show polyspecificity and bind unintended targets. This Fierce webinar brings together experts with experience in biotech, pharma, and the FDA to discuss the latest technologies and strategies to optimize IND safety data packages. Topics to be discussed include: … Read more

PHILADELPHIA – Integral Molecular announces the development of Humanized Chicken Antibody Technology (hCAT) and the incorporation of hCAT into the company’s industry-leading MPS antibody discovery platform for multipass membrane proteins. The innovation of hCAT lies in the ability to isolate fully humanized antibodies directly from immunized animals, reducing the time and effort needed for antibody … Read more