Broadly neutralizing antibodies from human survivors target a conserved site in the Ebola virus glycoprotein HR2–MPER region
FLYAK. 2018. NATURE MICROBIOLOGY 3, 670-677.
RESOURCES
Where research scientists come to find up to date resources on antibody discovery against challenging membrane protein targets.
Category: Mapping and Engineering
Probing the antigenicity of hepatitis C virus envelope glycoprotein complex by high-throughput mutagenesis
GOPAL, ET AL. 2017. PLOS PATHOGENS 13(12), E1006735.
High-throughput Protein Engineering Improves the Antigenicity and Stability of Soluble HIV-1 Envelope Glycoprotein SOSIP Trimers
SULLIVAN, ET AL. 2017. J VIROL 91(22), E00862-17.
Immunization-Elicited Broadly Protective Antibody Reveals Ebolavirus Fusion Loop as a Site of Vulnerability
ZHAO ET AL. 2017. CELL 169, 891-904.
Cooperativity Enables Non-neutralizing Antibodies to Neutralize Ebolavirus
HOWELL ET AL. 2017. CELL REP 19(2), 413-424.
Mapping the Human Memory B Cell and Serum Neutralizing Antibody Responses to Dengue Virus Serotype 4 Infection and Vaccination.
NIVARTHI ET AL. 2017. J VIROL 91(5), E02041-02056.
Neutralizing Monoclonal Antibodies Block Chikungunya Virus Entry and Release by Targeting an Epitope Critical to Viral Pathogenesis
JIN ET AL. 2016. CELL REPORTS 13(11): 2553-2564.
Rapid isolation of dengue-neutralizing antibodies from single cell-sorted human antigen-specific memory B-cell cultures
COX ET AL. 2016. MABS 8(1):129-140.
Neutralizing human antibodies prevent Zika virus replication and fetal disease in mice
SAPPARAPU ET AL. 2016. NATURE 540, 443–447.