SOLUTIONS FOR VIROLOGY AND VACCINE DISCOVERY

Enabling the discovery of vaccines and antiviral therapeutics against SARS-CoV-2, Dengue, Zika, and other viruses

Reporter Viruses

Epitope Mapping
MAb Specificity Testing

Reporter Virus Particle (RVP) Neutralizing Antibodies, Cell Lines, and Controls

We offer monoclonal antibodies that are validated as neutralization controls for RVP assays

Catalog No.
Description
Isotype
Immunogen
Applications
IM-CoV2-F06
SARS-CoV-2 broadly neutralizing antibody (including Omicron)*
Human IgG1
Wuhan-Hu-1 Spike RBD
Neutralization assay, FC
IM-CoV2-G06
SARS-CoV-2 broadly neutralizing antibody (including Delta)**
Human IgG1
Wuhan-Hu-1 Spike RBD
Neutralization assay, FC
IM-CKV063
Chikungunya neutralizing antibody
Human IgG1
Natural infection, MAbs bind E2
Neutralization assay, FC
IM-ZKV081
Zika neutralizing antibody
Human IgG1
Natural infection, MAbs bind E protein
Neutralization assay, FC

For research use only
FC- Flow Cytometry
*Neutralizes Wuhan-Hu-1, D614G, Alpha, and Omicron
**Neutralizes Wuhan-Hu-1, D614G, Alpha,  and Delta

SARS-CoV-2 and Other Neutralizing Monoclonal Antibodies

SARS-CoV-2 neutralizing antibodies, IM-CoV2-G06
SARS-CoV-2 neutralizing antibodies, IM-CoV2-F06

Negative Control RVPs with VSV

Catalog No.
RVP
Strain
RVP-1002
VSV with MLV core
Indiana
SARS-CoV-2 neutralizing antibodies, VSV G-protein
VSV RVPs function as a control for RVP experiments to differentiate specific versus non-specific effects on neutralization
  • RVPs display VSV-G protein
  • Compatible for use with all target cells including ACE2-HEK 293T
  • Available with luciferase or GFP reporter

Cell Lines

Catalog No.
RVP Compatibility
Transgene
Expression
Clonality
Origin Cell Line
C-HA102
SARS-CoV-2 RVPs
hsACE2
Stable
Monoclonal
HEK 293T
C-BD101
ZIKV, DENV RVPs
hsDC-SIGN
Stable
Monoclonal
BHK

Integral Molecular’s RVP and virology reagents are produced under stringent quality-controlled conditions.

With two decades of virology experience, Integral Molecular is the industry leader in providing RVPs for applications including antibody R&D and serum screening for vaccine clinical trials.

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