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SOLUTIONS FOR VIROLOGY AND VACCINE DISCOVERY
Enabling the discovery of vaccines and antiviral therapeutics against SARS-CoV-2, Dengue, Zika, and other viruses
Reporter Virus Particle (RVP) Neutralizing Antibodies, Cell Lines, and Controls
We offer monoclonal antibodies that are validated as neutralization controls for RVP assays
Catalog No. | Description | Isotype | Immunogen | Applications |
|---|---|---|---|---|
IM-CoV2-F06 | SARS-CoV-2 broadly neutralizing antibody (including first-generation Omicron variants) | Human IgG1 | Wuhan-Hu-1 Spike RBD | Neutralization assay, FC |
IM-CoV2-G06 | SARS-CoV-2 broadly neutralizing antibody (including Delta)** | Human IgG1 | Wuhan-Hu-1 Spike RBD | Neutralization assay, FC |
IM-CKV063 | Chikungunya neutralizing antibody | Human IgG1 | Natural infection, MAbs bind E2 | Neutralization assay, FC |
IM-ZKV081 | Zika neutralizing antibody | Human IgG1 | Natural infection, MAbs bind E protein | Neutralization assay, FC |
For research use only
FC- Flow Cytometry
*Neutralizes Wuhan-Hu-1, D614G, Alpha and first-generation Omicron variants (BA.1, BA.1.1, BA.2)
**Neutralizes Wuhan-Hu-1, D614G, Alpha, and Delta
SARS-CoV-2 and Other Neutralizing Monoclonal Antibodies
Negative Control RVPs with VSV
Catalog No. | RVP | Strain |
|---|---|---|
RVP-1002 | VSV with MLV core | Indiana |
VSV RVPs function as a control for RVP experiments to differentiate specific versus non-specific effects on neutralization
- RVPs display VSV-G protein
- Compatible for use with all target cells including ACE2-HEK 293T
- Available with luciferase or GFP reporter
Cell Lines
Catalog No. | RVP Compatibility | Transgene | Expression | Clonality | Origin Cell Line |
|---|---|---|---|---|---|
C-HA102
| SARS-CoV-2 RVPs
| hsACE2
| Stable
| Monoclonal
| HEK 293T
|
C-BD101 | ZIKV, DENV RVPs
| hsDC-SIGN
| Stable
| Monoclonal
| BHK
|
Integral Molecular’s RVP and virology reagents are produced under stringent quality-controlled conditions.
With two decades of virology experience, Integral Molecular is the industry leader in providing RVPs for applications including antibody R&D and serum screening for vaccine clinical trials.
