PSEUDOTYPED REPORTER VIRUS PARTICLES

Virology reagents for neutralization assays: ideal for therapeutic antibody and vaccine development

Critical virology reagents

20+ years virology expertise

Trusted by 100+ labs

RVP Technology    |    RVP Catalog    |      RVP Applications     |   Case Studies   |   Publications  |   FAQs

Reporter Virus Particles (RVPs): Pseudoviruses for Safe Neutralization Data

Reporter Virus Particles (RVPs) are non-replicating pseudoviruses for your BSL-2 lab. Use them in place of live virus for high-throughput viral infectivity and neutralization assays.
Cross-section schematic of pseudotyped lentiviral RVP. Viral envelope proteins stud the surface of a spherical lipid bilayer. Inside, a lentivirus heterologous core surrounds a reporter gene. Graph shows a SARS-CoV-2 pseudovirus neutralization assay, comparing serum from two patients against positive control monoclonal antibody and negative control serum.
  • Safe in a BSL-2 environment
  • Ready-to-use pseudotyped viruses
  • Quantitative (luciferase) or fluorescent (GFP) read-out
  • Quality-controlled critical reagents based on 20+ years of virology expertise

“SARS-CoV-2 RVPs really helped us a lot since we did not have much previous expertise in SARS. The user meetings were especially helpful.”

-YUFEI XIANG, UNIVERSITY OF PITTSBURGH SCHOOL OF MEDICINE

Product Offerings: The Most Extensive Catalog of Reporter Virus Particles

Cross-section schematics of RVP pseudoviruses for neutralization assays. Includes multiple coronaviruses, Influenza A and B, Filovirus, Henipavirus, Dengue, and Zika.

Learn more about our most popular products:

>    SARS-CoV-2 variant Reporter Virus Particles
>    Influenza Reporter Virus Particles
>    Filovirus Reporter Virus Particles
>    Dengue and Zika RVP case study

Using RVPs in Your Research: Scientific & Regulatory Information

The Integral Advantage: 20+Years of Virology Experience ​

Deep expertise in virology is at the core of Integral Molecular’s 20-year history, and we have co-authored over 70 peer-reviewed virology publications in journals including Cell, Science and Nature. With the support of NIAID, scientists at Integral Molecular have been on the forefront of combatting viral epidemics including COVID-19, Zika, Ebola, and Chikungunya. Meet our team.

Trusted by 100+ Laboratories for R&D and Clinical Trials ​

reporter virus particles

Case Studies & Publications: See how our customers have used RVPs ​

Publications Establishing RVPs as a Critical Reagent

Frequently Asked Questions

Ready To Get Started?

We have worked with more than 100 top biotech and pharmaceutical companies to help them succeed. Let’s talk about how we can help you.

Or call (215) 966-6061