Exposure of epitope residues on the outer face of the chikungunya virus envelope trimer determines antibody neutralizing efficacy.
FONG ET AL. 2014. JOURNAL OF VIROLOGY 88(24):14364-14379.
RESOURCES
Where research scientists come to find up to date resources on antibody discovery against challenging membrane protein targets.
Category: Membrane Proteins
Potent Dengue Virus Neutralization by a Therapeutic Antibody with Low Monovalent Affinity Requires Bivalent Engagement
EDELING ET AL. 2014. PLOS PATHOGENS 10(4):E1004072.
Origin and Differential Selection of Allelic Variation at TAS2R16 Associated with Salicin Bitter Taste Sensitivity in Africa
CAMPBELL ET AL. 2014. MOL BIOL EVOL 31(2):288-302.
Detection of Proton Movement Directly across Viral Membranes To Identify Novel Influenza Virus M2 Inhibitors.
SULLI ET AL. 2013. JOURNAL OF VIROLOGY 87(19):10679-10686.
High-throughput Alanine Scanning.
BERDOUGO AND DORANZ 2012. GENETIC ENGINEERING & BIOTECHNOLOGY NEWS VOL. 32, NO. 12.
Isolating Membrane Protein Antibodies
BERDOUGO ET AL. 2012. GENETIC ENGINEERING & BIOTECHNOLOGY NEWS VOL. 33, NO. 6.
Maturation of the Gag core decreases the stability of retroviral lipid membranes.
DAVIDOFF ET AL. 2012. VIROLOGY 433(2):401-409.
Probenecid inhibits the human bitter taste receptor TAS2R16 and suppresses the bitter perception of salicin.
GREENE ET AL. 2011. PLOS ONE 6 (5): E20123.
Antibodies against membrane protein targets.
BANIK ET AL. 2011. GENETIC ENGINEERING & BIOTECHNOLOGY NEWS VOL. 31, NO. 2.
