MPA – Deorphaning antibody panels using the Membrane Proteome Array
A collaborator developed a library of monoclonal antibodies capable of distinguishing among several
cell types by using a phenotypic screening approach.
RESOURCES
Where research scientists come to find up to date resources on antibody discovery against challenging membrane protein targets.
Category: Case Studies
MPA – How the Membrane Proteome Array Enabled Rapid Progression of a Neutralizing SARS-CoV-2 MAb
Integral Molecular In response to the COVID-19 pandemic, AboundBio developed potent neutralizing monoclonal antibodies (MAbs) against SARS-CoV-2.
Virology – SARS-CoV-2 RVPs and Live Virus Show Similar Neutralization Titers
Integral Molecular In response to the COVID-19 pandemic, researchers at the University of Pittsburgh raised a panel of high-affinity SARS-CoV-2 nanobodies.
Lipoparticles – CX3CR1 Case Study
Learn how Lipoparticles rescued a CX3CR1 discovery campaign and enabled a clinical stage antibody
MPS Antibody Discovery – Claudin 6 Case Study
Highly specific MAbs against the tight junction protein Claudin 6 for solid tumors
MPS Antibody Discovery – P2X7 Case Study
Agonist and antagonist MAbs targeting the P2X7 ion channel for autoimmune disorders
MPS Antibody Discovery – GLUT4 Case Study
Discovering antibodies against GLUT4, a complex 12-TM transporter
MPS Antibody Discovery – CB1 Case Study
Discovery of antagonist MAbs against the GPCR CB1 for treating NASH
Epitope Mapping – Covagen Case Study
Is the HER2 epitope of Fynomer C12 distinct from trastuzumab and pertuzumab?
