PUBLICATIONS

1. Endres, et al. 1997.Targeting of HIV- and SIV-infected cells by CD4-chemokine receptor pseudotypes. Science 278:1462-1464. (Abstract) (Reprint)
   This publication from the laboratory of James Hoxie demonstrates for the first time that complex membrane proteins, such as G protein-coupled receptors (GCPRs), can be incorporated into retroviruses while maintaining their native structure.
   
   
2. Balliet and Bates. 1998. Efficient infection mediated by viral receptors incorporated into retroviral particles. Journal of Virology 72:671-676. (Abstract) (Reprint)
   This publication from the laboratory of Paul Bates extends the work of Dr. Hoxie's group by incorporating additional membrane proteins, including a fourteen transmembrane amino acid transporter, into additional types of retroviruses.
   
   
3. Hoffman, et al. 2000. A biosensor assay for studying ligand-membrane receptor interactions: Binding of antibodies and HIV-1 Env to chemokine receptors. PNAS 97:11215-11220. (Abstract) (Reprint)
   This publication from the laboratories of Robert Doms and Joseph Rucker is the first to demonstrate the use of viral vectors as biochemical tools. The application of Lipoparticle technology to the biosensor enabled protein-protein interactions to be analyzed, including antibody and HIV Envelope (gp120) interactions with G protein-coupled receptors.